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Journal Articles


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Pergolizzi J, Ahlbeck K, Aldington D, Alon E, Collett B, Coluzzi F, Huygen F, Jaksch W, Kocot-Kępska M, Mangas AC, Margarit C, Mavrocordatos P, Morlion B, Müller-Schwefe G, Nicolaou A, Hernández CP, Sichere P, Varrassi G.

The chronic pain conundrum: should we CHANGE from relying on past history to assessing prognostic factors? Curr Med Res Opin. 2011 Dec 19


Taylor R, Raffa R, and Pergolizzi J.

Naltrexone extended-release injection: an option for the management of opioid abuse Substance Abuse and Rehabilitation 2011:2; 219–226


Pergolizzi J.

Quantifying the Impact of Drug-Drug Interactions Associated with Opioids The American Journal of Managed Care. 2011:17 (11). (S) 288-292


Pergolizzi J.

Chronic pain – moving from symptom control to mechanism-based treatment Current Medical Research & Opinion 2011: 27(10): 2079–2080


Blair R, Taylor R, Pergolizzi J, Tabor A.

Clinical Roundup: How Do You Treat Premenstrual Syndrome in Your Practice? Alternative and Complementary Therapies. August 2011, 17(4): 237-246



Varrassi G, Collett B, Morlion B, Kalso E, Nicolaou A, Dickenson A, Pergolizzi J, Schafer M, and Muller-Schwefe G.

Conference report Proceedings of the CHANGE PAIN Expert Summit in Rome, June 2011 Current Medical Research & Opinion 2011: 27 (10): 2061–2062


Pergolizzi J, Alegre C, Blake D, Alén JC, Caporali R, Casser HR, Correa-Illanes G, Fernandes P, Galilea E, Jany R, Jones A, Mejjad O, Morovic-Vergles J, Oteo Álvaro A, Radrigán Araya FJ, Simões ME, Uomo G.

Current Considerations for the Treatment of Severe Chronic Pain: The Potential for Tapentadol Pain Pract. 2011 Jul 29


Pergolizzi J, Alon E, Baron R, Bonezzi C, Dobrogowski J, Gálvez R, Jensen T, Kress HG, Marcus MAE, Morlion B, Perrot S, Treede RD.

Tapentadol in the management of chronic low back pain: a novel approach to a complex condition? Journal of Pain Research 2011:4: 203–210


Pergolizzi J, Raffa R, and Taylor R.

Prophylaxis of Postoperative Nausea and Vomiting in Adolescent Patients: A Review with Emphasis on Combination of Fixed-Dose Ondansetron and Transdermal Scopolamine Journal of Drug Delivery Volume 2011, Article ID 426813, 7 pages



Pergolizzi JV, Raffa RB, Tallarida R, Taylor R, Labhsetwar SA.

Continuous Multimechanistic Postoperative Analgesia: A Rationale for Transitioning from Intravenous Acetaminophen and Opioids to Oral Formulations Pain Pract. 2011 Jun 16



Pergolizzi J, Gan TJ, Plavin S, Labhsetwar S, Taylor R,

Perspectives on the Role of Fospropofol in the Monitored Anesthesia Care Setting Anesthesiology Research and Practice, vol. 2011, Article ID 458920



Pergolizzi J, Taylor R, and Raffa R.

“Extended-release Formulations of Tramadol in the Treatment of Chronic Pain” In Press: Expert Opin Pharmacother. 2011:12 (11)

Pergolizzi, J.

In response: urine drug screening and compliance Pain Pract. 2011 Mar; 11(2):199



Altorjay A; Melson T; Chinachoit T;Kett A; Aqua K; Levin J; Blackburn LM; Lane S; Pergolizzi JV

Casopitant and Ondansetron for Postoperative Nausea and Vomiting Prevention in Women at High Risk for Emesis: A Phase 3 Study. Arch Surg. 2011; 146(2):201-206



Pergolizzi JV, Labhsetwar SA, Puenpatom RA, Joo S, Ben-Joseph R and Summers KH.

Exposure to Potential CYP450 Pharmacokinetic Drug–Drug Interactions among Osteoarthritis Patients: Incremental Risk of Multiple Prescriptions. Pain Practice Article first published online: 28 DEC 2010



Leslie JB, Viscusi ER, Pergolizzi JV, and Panchal SJ.

Anesthetic Routines: The Anesthesiologist’s Role in GI Recovery and Postoperative Ileus Advances in Preventive Medicine Volume 2011, Article ID 976904, 10 pages



Pergolizzi F, Pergolizzi J III, Gan Z, Macario S, Pergolizzi JV, Ewin TJ, and Gan TJ.

Bullying in middle school: Results from a 2008 survey Int J Adolesc Med Health 2011; 23(1):11–18


Raffa RB, and Pergolizzi J.

The evolving understanding of the analgesic mechanism of action of flupirtine. Journal of Clinical Pharmacy and Therapeutics (2010) Article first published online: 28 NOV 2010



Müller-Schwefe, Jaksch W, Morlion B, Kalso E, Schafer M, Coluzzi F, Huygen F, Kocot-Kepska M, Mangas AC, Margarit C, Ahlbeck K, Orónska A, Mavrocordatos Collett B, Aldington , Nicolaou A, Pergolizzi J Varrassi G.

Commentary Make a CHANGE: optimizing communication and pain management decisions. Current Medical Research & Opinion Vol., No. , 2011, 1–8


Apfel C, Zhang K, George E, Shi S, Jalota L, Hornuss C, Fero K, Heidrich F, Pergolizzi J, Cakmakkaya O, and Kranke P.

Transdermal Scopolamine for the Prevention of Postoperative Nausea and Vomiting: A Systematic Review and Meta-Analysis Clinical Therapeutics. Vol. 32, No.12, 2010, 1-15.


Langley P, Mueller-Schwefe G, Nicolaou A, Liedgens H, Pergolizzi J, and Varrassi G.

The impact of pain on labor force participation, absenteeism and presenteeism in the European Union Journal of Medical Economics Vol. 13, No. 4, 2010, 662–672


Raffa, RB and Pergolizzi, JV.

Opioid Formulations Designed to Resist/Deter Abuse Drugs. 70(13):1657-1675, September 10, 2010



Pergolizzi J, Labhsetwar S, Puenpatom A, Joo S, Ben-Joseph R, Summers K.

Prevalence of Exposure to Potential CYP450 Pharmacokinetic Drug – Drug Interactions among Patients with Chronic Low Back Pain Taking Opioids. Pain Practice Article first published online: 26 AUG 2010



Raffa RB and Pergolizzi, J.

Deciphering the mechanism(s) of action of natural products: analgesic peroxide oil as example In Press: Journal of Clinical Pharmacy and Therapeutics (2010).


Langley P, Muller-Schwerfe G, Liedgens H, Pergolizzi J, Varrassi G.

The societal impact of pain in the European Union: health-related quality of life and healthcare resource utilization Journal of Medical Economics Vol. 13, No. 3, 2010: 571-581


Raffa RB, Pergolizzi JV, and Tallarida RJ.

The Determination and Application of Fixed-Dose Analgesic Combinations for Treating Multimodal Pain The Journal of Pain, 2010: 11(8): 701-709


Apfel CC, Cakmakkaya OS, Martin W, Richmond C, Macario A, George E, Schaefer M and Pergolizzi JV.

Restoration of disc height through non-invasive spinal decompression is associated with decreased discogenic low back pain: a retrospective cohort study BMC Musculoskeletal Disorders 2010, 11:155



Raffa RB, Pergolizzi JV, Segarnick DJ and Tallarida RJ.

Oxycodone combinations for Pain Relief Drugs of Today 2010, 46(6): 379-398


Hochman JS, Pergolizzi J.

Cohort study finds nine times increased overdose risk (fatal plus non-fatal) in patients receiving 100 mg/day for 90 days compared with 1-20 mg/day opioids for chronic non-cancer pain, but wide CI and possibility of unmeasured confounders Evid Based Nurs. 2010; 13(2):55-6.


Arbuck D, Gharibo C, Labhsetwar S, Berdos F, Pergolizzi J

Management of Opioid Tolerability and Related Adverse Effects Journal of Medicine 2010; 3(1):1–10


Pergolizzi J, Pappagallo M, Raffa R, Gharibo C, Phillips R, Desjonquères S, and Tabor A.

Preliminary Observations of a Novel Topical Oil with Analgesic Properties for Treatment of Acute and Chronic Pain Syndromes Pain Practice 2010:3; 201-213


Morlion B, Pergolizzi J, Raffa R

European perspectives on upcoming analgesics: What do they have that we don’t—and what do they think about them? Techniques in Regional Anesthesia and Pain Management 2010:14; 86-98.


Pergolizzi J, Pappagallo M, Stauffer J, Gharibo C, Fortner N, De Jesus MN, Brennan MJ, Richmond C, Hussey D; The Integrated Drug Compliance Study Group (IDCSG).

The Role of Urine Drug Testing for Patients on Opioid Therapy Pain Pract. 2010; 10(6):497-507

Singla NK, Singla SK, Chung, F, Kutsogiannis DJ, Blackburn L, Lane SR, Levin J, Johnson B, Pergolizzi, J.

Phase II Study to Evaluate the Safety and Efficacy of the Oral Neurokinin-1 Receptor Antagonist Casopitant (GW679769) Administered with Ondansetron for the Prevention of Postoperative and Post discharge Nausea and Vomiting in High-risk Patients Anesthesiology 2010; 113:1–1

Varrassi G, Müller-Schwefe , Pergolizzi J , Orónska A, Morlion B, Mavrocordatos Margarit C, Mangas , Jaksch W, Huygen , Collett B, Berti M, Aldington, Ahlbeck K.

Pharmacological treatment of chronic pain – the need for CHANGE. Current Medical Research and Opinion 2010: 26(5): 1231-1245

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